Structure-guided discovery of 2-aryl/pyridin-2-yl-1H-indole derivatives as potent and selective hepsin inhibitors. http://www.ncbi.nlm.nih.gov/pubmed/26421993
Benzimidazole derivatives as potential dual inhibitors for PARP-1 and DHODH.
Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion. http://www.ncbi.nlm.nih.gov/pubmed/26165838
Title: AFN-1252 is a potent inhibitor of enoyl-ACP reductase from Burkholderia pseudomallei – Crystal structure, mode of action, and biological activity.
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